The Colts host the Dolphins in Week 1 on Sunday, Sept. 7, 2025, at 1:00 PM ET at Lucas Oil Stadium. The game airs on CBS with Andrew Catalon, Charles Davis, and AJ Ross on the call. You can stream it on Paramount+ if your local CBS station carries the game. The Colts are 1.5-point favorites and the total is 46.5.